There are compatibility issues to consider when configuring the IP version for cells.
WebSphere Application Server has support for Internet Protocol Version 4 (IPv4) and IPv6. However, on the i5/OS platform, WebSphere Application Server V6 supports IPv4 only.
When defining a node, specify the host name as a string or as a 32-bit numerical address.
When you create a new profile, you can optionally specify the host name for the profile by using the -hostName parameter. If you do not specify the host name, the host name for the profile defaults to the fully qualified host name for the iSeries server. If you choose to use the -hostName parameter and want to specify the IP address for your iSeries server, specify the valid 32-bit numerical address.
WebSphere
Application Server uses multicast broadcasting at the node level to allow
a node agent to discover the managed processes in the node. IPv4 and IPv6
addresses are not compatible. Therefore, to allow a WebSphere Application
Server node to run after initial installation, both IPv4 and IPv6 multicast
addresses are initially defined in the node agent configuration, and when
a node agent starts, both addresses are tried in sequence. Delete the NODE_IPV6_MULTICAST_DISCOVERY_ADDRESS
address after installation because, because limiting multicast discovery to
the known protocol, the node agent runs more efficiently.